System Overload has been a big topic in clinic these past few weeks so, I decided to share some insights and education to help you see the bigger picture and provide hope that there is a way forward.
Does this sound familiar?
You’ve probably wondered: “How did I become allergic to life?”
I hear this all the time. You’ve become a detective in your own kitchen, bathroom, and brain. But no matter how much you eliminate, filter, or avoid, the symptoms creep back in—rashes, anxiety, fatigue, insomnia, food reactions, chemical sensitivity, and that 3 a.m. wake-up is now part of your nightly routine.
If your body is reacting to everything, it may be because your immune system is overwhelmed, your detox systems are jammed, and your mast cells (AKA mastocytes) are stuck in panic mode.
Meet the Mast Cells – Your Body’s Overzealous First Responders
Mast cells live in your gut, brain, lungs, skin, sinuses, bladder—basically anywhere your body meets the outside world. Their job is to scan every incoming signal and decide whether it’s friend, foe, or full-blown emergency.
When you’ve been exposed to too many stressors and or toxins, mast cells lose their nuance. Now everything looks like a threat.
Normally, mast cells help you by:
But when this system gets dysregulated, it’s like your internal fire alarm won’t stop screeching—even when nothing is burning.
Mast cell chaos can show up as:
This isn’t random—it’s a pattern. It’s your body sending out an SOS because the load is too high and your drainage systems are jammed.
Histamine isn’t the enemy. It helps regulate stomach acid, brain focus, mitochondrial function, immune signaling, even wound healing. The trouble comes when your body can’t clear histamine effectively.
Two main enzymes do the job:
Mold and toxin exposure, gut damage, or genetics can slow them down. Add stress, hormone shifts, gut infections, high-histamine foods, or certain medications, and suddenly the “histamine bucket” overflows.
If you’ve found yourself reacting to avocados, bone broth, or kombucha—it’s not because you’re suddenly intolerant to health foods. It’s because your gut and enzymes can’t process histamine right now.
What you need isn’t restriction forever—it’s restoring your gut terrain and mucosal barrier, so your body remembers how to regulate again.
The Hopeful Truth
You are not doomed. You are not broken. Mast cell chaos is not a permanent identity. Once you reduce the toxic load—and create safety in your system, your mast cells will calm down. Your tolerance will return. And so will your joy, resilience, and glow.
The Fix – Calm the Chaos, Restore Flow
Healing isn’t about pushing harder—it’s about creating the right conditions for your body’s innate brilliance. Healing to be effective needs to be done in a sequence so that you build resilience.
You can’t detox in fight-or-flight. Anchor safety with vagal support (breathing, humming), gentle movement, grounding, meditation, gratitude journaling and safe relationships. Healing happens in parasympathetic mode. Here is a copy of my breathwork info.
This is the most important step that many miss or do not give it the attention it deserves. Adaptogens like Ashwagandha and minerals can also be supportive
Open Drainage Pathways
Think of it like unclogging the drains before deep cleaning the house:
Support Histamine Breakdown
Bind Gently
Start with low-dose binders with drainage support. Binders help take out the trash safely.
Sweat, Sauna, Skin Brushing
Only once detox is flowing. 4-6 weeks after you have started with consistent Nervous system support
Support Mitochondria
Build cellular energy before going after pathogens
Remember
As always have a healthy week and reach out if you need support. BOOK ONLINE
Dr Pia
